Learning objectives
<br />Identify health and safety risks related to work activities:<br /><br /><br />Assess the risks linked to the organisation of work and to the exposure to chemical, physical and biological agents:<br /><br />Discuss the meaning and the use of environmental exposure limits<br /><br />Describe the main standards and legal provisions on medicine, hygiene and safety in the workplace.<br /><br />Define the meaning of the main parameters for the assessment of the toxicological properties of chemical substances <br /><br />Interpret the meaning of: dose, effect, toxicokinetics, absorption, distribution, metabolism, elimination, toxicodynamics, target tissue/organ, metabolic activation, latency period:<br /><br />Define the meaning and understand the use of biological exposure indicators<br /><br />Assess the main dose and effect indicators and their modification depending on the different occupational risks <br /><br />Acute and chronic intoxications;<br /><br />Identify the main occupational diseases;<br /><br />Organ pathology;<br /><br />Occupational neoplastic diseases;<br /><br />Assess concausal role of the working activity in the genesis of common diseases;<br /><br />Identify clinical signs of medical emergencies occurring as consequences of acute exposure;<br /><br />Concausal effect of the working activity in the genesis of common diseases such as pulmonary diseases, osteoarthropathies, gastroenteropathies, cardiopathies, neurological, psychiatric and psychosomatic diseases;;
Prerequisites
<br />Pre-clinical disciplines, in particular:<br />Human physiology<br />General Pathology:<br />Medical semiotica
Course unit content
<br />Syllabus of the integrated course of Occupational Medicine <br />Faculty of Medicine and Surgery<br /> <br />§1 The role of occupational medicine and its relationship with other medical and social disciplines<br /> <br />§2 Italian legislation and European Directives in the field of prevention and safety in the workplace<br /> <br />§3 Occupational medical history<br /> <br />§4 Elements of occupational psychology<br /> <br />§5 Risk factors and occupational activities<br />5.1 The concept of danger and risk<br />5.2 Risks linked to occupational exposure to:<br /> 5.2.1 chemical agents<br /> 5.2.2 physical agents<br /> 5.2.3 biological agents<br /> 5.2.4 behavioural factors<br />5.3 Occupational injuries and diseases<br /> <br />§6 Meaning of the main parameters for the characterization of the toxicity of chemical substances and general principles of risk assessment<br />6.1 The concept of<br /> 6.1.1 Dose<br /> 6.1.2 Effect<br /> 6.1.3 Toxicokinetics (absorption, distribution, metabolism, elimination)<br />6.1.4 Toxicodynamics (target tissue/organ, metabolic activation, mechanisms of action, latency period)<br />6.2 Identification of the dangers, exposure assessment, meaning and use of the limits for environmental exposure (MAK, TLV)<br />6.3 The role of individual susceptibility<br />6.4 Meaning and use of biological indicators of exposure<br /> <br />§7 Action mechanisms and effects of the following toxic substances.<br /> 7.1 Solvents<br />7.1.1 aliphatic hydrocarbons<br />7.1.2 aromatic hydrocarbons<br />7.1.3 chlorinated hydrocarbons<br /> 7.2 Metals and metalloids<br />7.2.1 Lead (Pb)<br />7.2.2 Trivalent and hexavalent chromium (Cr)<br />7.2.3 Cadmium (Cd)<br />7.2.4 Mercury (Hg) and its compounds<br />7.2.5 Manganese (Mn)<br />7.2.6 Arsenic (As)<br /> 7.3 Pesticides<br />7.3.1 organophosphorics<br />7.3.2 organochlorates<br />7.3.3 pyrethroids<br /> <br />§8 Acute and chronic intoxications caused by metals<br /> <br />§9 Chemical cancerogenesis mechanisms and recognition of the main occupational cancers:<br /> 9.1 bladder cancers<br /> 9.2 cancers of the paranasal sinuses<br /> 9.3 liver cancers<br /> 9.4 lung cancers<br />9.5 mesothelioma<br />9.6 hematopoietic cancers and dyscrasias<br /> <br />§10 Neurotoxicity mechanisms and main toxic, central and peripheral neuropathies<br /> <br />§11 Occupational diseases and work-related diseases<br /> <br />§12 Concausal role of the working activities in the genesis of non occupational diseases<br /> <br />§13 Organ diseases<br />13.1 Pulmonary diseases<br /> 13.1.1 Allergic asthma<br /> 13.1.2 Extrinsic allergic alveolitis<br /> 13.1.3 Chronic obstructive bronchitis<br /> 13.1.4 Pneumoconiosis<br /> 13.2 Nephropathies<br /> 13.3 Hepatopathies<br /> 13.4 Hemopathies<br /> 13.5 Osteoarthropathies<br />§14 Industrial noise and auditory damage<br /> <br />§15 Health surveillance in workers exposed to risks<br /> <br />§16 Preventive and periodical health controls
Full programme
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Bibliography
<br />Vito Foa, Luigi Ambrosi <br />Medicina del Lavoro, 2a edizione<br />Utet, 2003 - ISBN 8802059764<br /> <br />Duilio Casula <br />Medicina del Lavoro, 3a edizione<br />Monduzzi, 2003<br /> <br />Giovanni Perrelli, Giorgio Scansetti, P.Giorgio Piolatto. <br />Medicina del Lavoro, 1a edizione<br />Minerva Medica, 2000- ISBN 8877113510
Teaching methods
<br />The integrated course includes the attendance of:<br />Oral lectures.<br />occupational medicine and industrial hygiene seminars<br />on-site inspections of workplaces <br />The learning progress of the students is assessed through an oral examination<br /> <br /><br />Teachers: Proff. Innocente Franchini, Antonio Mutti, Enrico Bergamaschi, Massimo Corradi, Luisella Selis
Assessment methods and criteria
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Other information
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