Learning objectives
<br />This course aims to provide the informations and the scientific underground to approach correctly the methodology in Clinical Biochemistry. The purpose is a correct use and development of diagnostic products for Clinic\al Biochemistry and of devices for the collection, treatment and storage of biological samples.
Prerequisites
<br />Besides the obligatory prerequisites, it is appropriate that the student is able to manage the basic concepts of Biochemistry and Physiology.
Course unit content
<br />The biological sample: characteristics, instruction for optimal collection, treatment and conservation (avoiding pre-analytical variation). <br />The main analytical techniques and instrumentations to evaluate the molecules of interest in Clinical Chemistry. Analytical and post-analytical variability affecting the laboratory data. Clinical laboratory quality assurance.<br />Current waived laboratory test. Criteria for test waiving. Kits for diagnostic tests. Evolution Point of care testing (POCT) technology. Quality control in POCT. <br />Principles to detect the markers of organ function and lesion; analytical procedures and clinical correlations. <br />Methodology of therapeutic drug monitoring, detection of toxic compounds, abuse substances and of sport doping.
Full programme
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Bibliography
<br />R.A. Sacher, R.A. McPherson Interpretazione clinica degli esami di laboratorio Ed. McGraw-Hill, New York<br /> <br />L. Spandrio. Biochimica Clinica. Ed. Sorbona – Milano.
Teaching methods
<br />The final oral examination is about the topics of the course; the student needs to demonstrate to have understood and to be able to manage the essential meanings of every section of the program.
Assessment methods and criteria
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Other information
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