Learning objectives
<br />In the context of the integrated course, the course is proposed to supply to the students general concepts on the causes and the mechanisms that carry to the diseases. In particular, general knowledge about the chemical and physical causes of diseases and concepts of cellular pathology will be supply. More particularly, the student will have to acquire knowledge about inflammation, neoplasia, genetic diseases, genetic deafness, diabetes, atherosclerosis, diseases of the blood and alterations of the haemostasis<br />
Prerequisites
<br />It is advised to have supported the examinations of the previous year
Course unit content
<br />Concepts of aetiology and pathogenesis <br /> Chemical and physical causes of diseases<br /> Genetic damage. Mutations. <br /><br />Hereditary diseases <br />Modality of transmission of the pathological characters. <br />Monogenic hereditary diseases: examples. <br />Hereditary deafness<br />Multifactorial inheritance <br />Chromosomic aberrations <br /><br />Concepts and mechanisms of cellular pathology <br />Reversible and irreversible cellular damage. <br />Necrosis and apoptosis<br /><br />Ischemic damage<br /> Inflammation<br />Signs and phenomena of the acute inflammation <br />Inflammatory exudates <br />Phagocytoses <br />Chemical inflammatory mediators<br />Chronic inflammation<br />The fever<br /> Alterations in the proliferative state<br />Cell cycle<br />Hypertrophy <br />Hyperplasia <br /> Neoplasia<br />Nomenclature <br />Epidemiologia <br />Grading and staging <br />Differences between benign and malignant tumors <br />Neoplastic progression <br />Molecular bases of the neoplasie <br />Metastasis <br /> Physiopatology of the blood and the haemostasis <br />Constitution of the blood <br />Emopoiesi<br />Anemias <br />Haemostasis and its alterations <br /> Diabetes <br /> Arterial hypertension<br /> Atherosclerosis<br />
Full programme
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Bibliography
<br />One text chosen between the following:<br /> <br />1. Spector e Axford, Introduzione alla Patologia Generale, CEA<br />2. Woolf, Patologia Generale – Meccanismi della malattia, Idelson-Gnocchi
Teaching methods
<br />Frontal lesson with the use of supports audiovisual, argument in classroom with the students, supply of the audiovisual aids, talks with the student upon request. <br /> <br />The final appraisal involves one oral verification according to the calendar of examination of the Integrated Course. <br />
Assessment methods and criteria
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Other information
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