Learning objectives
students are expected to learn the general principles of food and xenobiotic toxicology as well as the toxicology of certain substances classed as doping. The main principles of toxicokinetics and toxicodynamics in order to find out modes of assumption, digestion, absorption , distribution, metabolism and elimination of the main toxins. Chemical characteristics, sources of contamination, mechanism of action and elimination routes of the main toxins. Chemical characteristics, mechanism of action, efficacy, toxic components and elimination phases of doping drugs (beta-agonists and anabolic steroids). Techniques for obtaining and producing technological proteins, with particular emphasis on yeast lysates and their use in muscular protein anabolism..
Prerequisites
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general and inorganic chemistry; organic chemistry
Course unit content
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principles of toxicokinetics and toxicodynamics; <br />
main xenobiotics contained in food: mycotoxins (aflatoxins, ochratoxin), pesticides (organochlorates, organophosphorics, carbamates), nitrites and nitrates, heavy metals (cadmium, mercury, fluorine); <br />
drugs and doping: toxic aspects of beta-agonists and anabolic steroids; <br />
nutrition and muscular hypertrophy: technological proteins, yeast lysates;
Full programme
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Bibliography
Casarett & Doull's. Tossicologia. Ed. AMSI
Teaching methods
classroom lectures with the use of audiovisual aids (transparencies, video projector and power point programs, photocopies and scientific articles). Written test on all the chapters covered during the course with final oral assessment.
Assessment methods and criteria
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Other information
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