Learning objectives
To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.
Prerequisites
Pharmacology exam
Course unit content
<br />General part<br />· First principles of toxicity <br />· Mechanisms and tests of toxicity <br />· ADME of toxic substance <br />· Metabolism of xenobiotics <br />· Cancerogenesis, teratogenesis and mutagenesis<br />· Experimental toxicology and evaluation of toxicological risks. Poisons and Antidotes.<br />· Metals, Solvents, Pesticides, IPA, PCOD, PCB <br />· Enviromental toxicoogy <br />· Alimentary toxicology <br />· Occupational toxicology <br />· Toxicology of biotecnological products
Full programme
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Bibliography
<br />CASARETT & DOULL’S: "Tossicologia: fondamenti dell’azione delle sostanze tossiche", Ed. EMSI,<br />Roma.<br />GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"<br />DOLARA: "Tossicologia generale ed ambientale", Ed. Piccin, Padov<br />ERNEST HODGSON: “Tossicologia Moderna”, EdiSES<br />W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.<br />C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”, Piccin
Teaching methods
The oral examination will be about the entire program. Students have to show to have a good comprension of principal parts of each topic.
Assessment methods and criteria
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Other information
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