Learning objectives
Acquisition of the current viral gene manipulation techniques relative to gene therapy.
Prerequisites
Students are required to have a knowledge of basic molecular biology.
Course unit content
Viral Vectors in gene therapy and immunotherapy <br />
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Retrovirus: <br />
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a) Molecular aspects of replication <br />
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b) Vector structure: oncoretrovirus (MMLV) and lentivirus (HIV) <br />
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c) Packaging strategies <br />
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d) Targeting and pseudo-typification strategies and mechanisms (VSV-G) <br />
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e) Cell transduction and expression control <br />
Full programme
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Bibliography
no
Teaching methods
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Assessment methods and criteria
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Other information
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