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Università degli Studi di Parma Università degli Studi di Parma
University of Parma
Course catalogue
Università degli Studi di Parma
course catalogue

BIOTHERMODYNAMICS
cod. 23807

borrowed from Corso di TIPO in CDS 1109 - BIOTERMODINAMICA - cod. 23807
Academic year 2008/09
1° year of course - First semester
Professor
Academic discipline
Chimica fisica (CHIM/02)
Field
Discipline applicate alle biotecnologie
Type of training activity
Basic
20 hours
of face-to-face activities
2 credits
hub:
course unit
in
lectures timetable unavailable
exam calls

Integrated course unit module: MOLECULAR MECHANISMS OF DRUG ACTION

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Learning objectives

The course aims at providing students with the thermodynamic concepts for the understanding the energy interconversion in biological systems and the interaction of ligands with biological macromolecules

Prerequisites

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Course unit content

<p> The laws of thermodynamics. Application of thermodynamic principles to chemical and biological systems. Calorimetry and biocalorimetry. <br />
Thermodynamic properties of solutions and applications, phase equilibria, osmotic pressure, membrane equilibria. <br />
Chemical equilibrium, thermodynamics of chemical reactions in solution, proton binding: pH behaviour of biomolecules, binding equilibria, binding curves. <br />
Bioenergetics, molecules through membranes: transport modes, coupled reactions. <br />
Intermolecular forces, van der Waals forces, potential energy, hydrogen bond, hydrophobic interactions. <br />
</p>

Full programme

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Bibliography

<p>- P. W. Atkins, J. De Paula, Chimica Fisica Biologica 1, prima edizione italiana, Zanichelli, Bologna, 2007. <br />
- P. W. Atkins, J. De Paula, Chimica Fisica, quarta edizione italiana, Zanichelli, Bologna, 2004. <br />
- A.G. Marshall, Biophysical Chemistry, Wiley & sons, New York. <br />
- K.E. Van Holde, Physical Biochemistry, Prentice-Hall, Englewood Cliffs. <br />
- David G. Nicholls Bioenergetics Academic press, inc. <br />
- Scientific reviews on specific topics . <br />
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</p>

Teaching methods

During teaching activity the students can take two written "in itinere" tests or, alternatively, an oral examination on the whole syllabus during normal examination sessions.

Assessment methods and criteria

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Other information

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