STRUCTURE AND FUNCTION OF BIOMOLECULES
cod. 1000151

Academic year 2008/09
1° year of course - First semester
Professor responsible for the course unit
ZUCCOTTI Maurizio
integrated course unit
5 credits
hub:
course unit
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Learning objectives

<span class="datirigaalto">To provide the bases for the comprehension and the study of the molecular mechanisms of membrane transport.<br />
<br />
</span><span class="datirigaalto">Acquisition of the knowledge on:<br />
- Cytological and molecular characteristics of the mitotic and meiotic cell cycle;<br />
- Cytological and molecular mechanisms that regulate cell differentiation during preimplantation development<br />
- Totitpotent, pluripotent, multipotent and unipotent stem cells;  stem cell plasticity;<br />
- Cell reprogramming.</span><br />
<span class="datirigaalto"><br />
</span><span class="datirigaalto">Knowledge of the molecular models underlying the functions of the chemosensory systems<br />
<br />
</span><span class="datirigaalto">The course is aimed to give students basic understanding of physiological mechanisms involved in homeostatic balance. Specific examples will be proposed to highlight the pivotal role of the hypothalamus in integrative processes.<br />
</span><span class="datirigaalto"><span lang="EN-GB" style="font-family: Arial;"><br />
Give students a basic knowledge of the principles and practise of the most important methods to determine the structure, the conformational stability and dynamics of proteins in solution.</span></span><br />
<span class="datirigaalto"><br />
<br />
</span>

Prerequisites

<span class="datiriga">Knowledge of basic biochemistry and cell biology is required</span>

Course unit content

 Module Prof. Maurizio Zuccotti<br />
<span class=""datirigaalto"">Acquisition of the knowledge on:<br />
- Cytological and molecular characteristics of the mitotic and meiotic cell cycle;<br />
- Cytological and molecular mechanisms that regulate cell differentiation during preimplantation development<br />
- Totitpotent, pluripotent, multipotent and unipotent stem cells;  stem cell plasticity;<br />
- Cell reprogramming.<br />
<br />
Module Prof. Giancarlo Gazzola<br />
</span><span class="datiriga">Biomembrane composition, structure and turnover. Transport kinetics. Structure and function of transport proteins that form, propagate or dissipate solute gradients. Regulation of plasma membrane transport. Selected techniques in membrane transport. </span><br />
<span class=""datirigaalto""><br />
Module Prof. Roberto Tirindelli<br />
</span><span class=""datirigaalto"">Knowledge of the molecular models at the base of the functions of the chemosensory systems<br />
<br />
Module Prof. Giuseppina Basini<br />
</span><span class=""datirigaalto"">The course is aimed to give students basic understanding of physiological mechanisms involved in homeostatic balance. Specific examples will be proposed to highlight the pivotal role of the hypothalamus in integrative processes. <br />
<br />
Module Prof. Lorella Franzoni<br />
</span><span class=""datirigaalto""><span lang=""EN-GB"" style="">Considering the significant development and relevance of the structural proteomics, this course is designed to give students a basic knowledge of the principles and practise of the most important methods to determine the structure, the conformational stability and dynamics of proteins in solution.</span></span>

Full programme

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Bibliography

<span class=""datiriga"">Sherwood, Klandorf, Yancey <br />
Fisiologia degli animali - dai geni agli<br />
<br />
Article given by the teachers<br />
<br />
</span><span class="datiriga">Proper reference to the texts of biochemistry and cell biology used in previous courses is recommended. Lectures will be supported by slides and scientific literature, which will be provided to the students.</span>

Teaching methods

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Assessment methods and criteria

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Other information

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