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University of Parma
Course catalogue
Università degli Studi di Parma
course catalogue

MICROBIAL GENOMICS - REVERSE GENETICS
cod. 15440

Academic year 2008/09
1° year of course - Second semester
Professor responsible for the course unit
LODI Tiziana
integrated course unit
5 credits
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course unit
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lectures timetable unavailable
exam calls

Course unit structured in the following modules:

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Learning objectives

Aims of the course is the study of genetic approaches applied to  genomics and functional analysis in microorganisms. Particular attentions will be paied to yeast, a model organism in fundamental and biotechnologic applications. 

Prerequisites

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Course unit content

Forward and reverse genetics.  Functional analysis in yeast: cloning of yeast gene by functional complementation; functional analysis by construction of gene deletion mutants; analysis of essential genes; yeast genomics.<br /> <br />Gene products interaction: multicopy suppressors; synthetic letals.<br /> <br />Yeast as a model organism in the study of mitochondrial  genetics: maternal genetics; petite  mutants; nuclear and mitochondrial pet mutants;  mitochondrial  genome organization; mitochondrial biogenesis.<br /> <br />Yeast as a model organism in the study of mitochondrial diseases<br /> <br />Metabolic engeneering in yeast and other microorganisms <br /> <br />Methods for functional analysis in other organisms: in Drosophila, in plants<br /> 

Full programme

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Bibliography

Original papers selected by the teacher

Teaching methods

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Assessment methods and criteria

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Other information

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