TRANSGENIC ANIMAL
cod. 13549

Academic year 2009/10
2° year of course - Second semester
Professor
Academic discipline
Genetica (BIO/18)
Field
Ambito aggregato per crediti di sede
Type of training activity
Hub-specific activity
32 hours
of face-to-face activities
4 credits
hub:
course unit
in - - -

Learning objectives

Basic knowledge of techniques currently used for the genetic modification in superior animals in order to: <br />
<br />
Improve physiological and anatomical features; <br />
Production of proteins of pharmaceutical interest (animal pharming); <br />
Development of animal systems for studying human pathologies; <br />
Use of transgenic animal for xenotransplants; <br />
Ethic, social, legal and environmental implications, related to the introduction of transgenic animals, will be evaluated; <br />
Possible alternatives to the use of transgenic animals in applied and basic research will be also considered. <br />
<br />

Prerequisites

Basic knowledge of embryology (cellular and biochemical basis of fertilization, segmentation and differentiation) and molecular genetics.<br />

Course unit content

Explanation of modern techniques of mutagenesis, such as zygote microinjection, ES cells technology, cloning, aimed to modify the genome of both laboratory and bred animals.

Full programme

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Bibliography

<br />
Biologia dello sviluppo, Gilbert (Zanichelli) Animal breeding Technology for the 21st century Clark (Harwood academic publishers)

Teaching methods

Multiple choice test and an essay about one of the topics covered during the course.<br />

Assessment methods and criteria

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Other information

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