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University of Parma
Course catalogue
Università degli Studi di Parma
course catalogue

MOLECULAR BIOLOGY
cod. 02617

Academic year 2008/09
2° year of course - First semester
Professor
Academic discipline
Biologia molecolare (BIO/11)
Field
Interdisciplinarieta e applicazioni
Type of training activity
Related/supplementary
32 hours
of face-to-face activities
4 credits
hub:
course unit
in - - -
lectures timetable unavailable
exam calls
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Learning objectives

Provide students in the second year of the advanced course the fundamental concepts regarding the molecular mechanisms of transmission of genetic information

Prerequisites

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Exams in general chemistry, preparatory biochemistry, physical biochemistry and general biology

Course unit content

<br />- Genes and chromosomes: chromosomal elements, dimension and structure of the DNA molecule, supercoiling of DNA, chromatin and nucleotide structure. <br />
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- Metabolism of DNA: replication, repair, recombination. <br />
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- Metabolism of RNA: DNA-dependent synthesis of RNA, RNA modifications following transcription, RNA-dependent RNA and DNA synthesis <br />
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- Protein metabolism: genetic code, protein synthesis, transport to destination and protein degradation. <br />
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- Regulation of genetic expression: principles of genic regulation, regulation of genic expression in prokaryotes, regulation of genic expression in eukaryotes. <br />
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- Technology of recombinant DNA: DNA cloning: basic techniques, isolating a gene from a cellular chromosome, applications of recombinant DNA. <br />
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Full programme

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Bibliography

Nelson, Cox: I principi di biochimica di Lehninger, 3. ed., Zanichelli 2002.<br />
Watson et al. Molecular biology  of the gene, V/e Benjamin Cummings Pub. Co. 2004

Teaching methods

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Assessment methods and criteria

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Other information

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