Learning objectives
<br />The objective of the course is to give the tools to perform simple laboratory operations and to become familiar with the most common organic compound purification and characterisation techniques; a further objective is to train the student to the effectuation of simple organic reactions.<br />
Prerequisites
<br />The arguments Knowledge of developed in the General and Inorganic Chemistry course and in Organic Chemistry course.<br />
Course unit content
<br />Programma: The organic chemistry laboratory: safety regulations; laboratory equipment: risks and use; laboratory solvents, industrial solvents and their use. Spectroscopy techniques (NMR, FT-IR, UV-Vis) and Mass Spectrometry: basic concepts; examples of structural determination through the NMR spectroscopy. Laboratory separation techniques: purification of solids and purity criteria; the solvent choice e the melting point determination; extraction techniques of organic compounds; natural product extraction; basic and acid substances extraction; chromatographic separations; the choice of the eluant, thin layer chromatography, column chromatography, gas chromatography; distillation techniques: simple distillation and fractional distillation. Laboratory experiences: organic compound purification through recrystallisation; caffeine extraction from tea leaves; organic product separation through acid-base extraction; ethyl acetate and butyl acetate separation through fractional distillation and gas-chromatographic analysis. Thin layer chromatography, spinach extract separation on column chromatography: spectrophotometric UV-Vis analyses; alkane chlorination: chemical assays and gas chromatographic analyses; Friedel-Crafts acylation and product analysis through NMR spectroscopy; analysis through chemical assays.<br /><br />
Full programme
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Bibliography
<br />R.M. ROBERTS, J.C. GILBERT, L.B. RODEWALD, A.S.<br />WINGROVE Chimica Organica<br />Sperimentale, Zanichelli.<br /><br />M.D'ISCHIA- Chimica Organica Sperimentale--PICCIN <br />R.M. Silverstein, F.X. Webster, 'Identificazione Spettroscopica di Composti Organici' Casa Editrice Ambrosiana<br />
Teaching methods
<br />FRONTAL LESSONS AND NMR EXERCISES - 30 ORE <br />NINE LABORATORY EXPERIENCES, EACH FOUR HOURS<br />
Assessment methods and criteria
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Other information
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