Learning objectives
Course aims: To provide the students the basic knowledge on functional and defensive role of the inflammatory process, on its cellular and molecular regulation and its evolutive aspects; the students will achieve the fundamental concepts on pathogenesis of immune-mediated diseases (hypersensitivity, autoimmunity and immunosuppression). <br />
Prerequisites
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Course unit content
<p> CONTENT OF THE MODULE OF GENERAL PATHOLOGY AND IMMUNOLOGY II <br />
(3 CFU: 24 hours) (Lecturer : Prof. Paolo Borghetti) <br />
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The response to cell damage: inflammation <br />
- General features, ethiology and evolutive aspects of inflammation <br />
- Dynamics and regulation of acute and chronic inflammation. <br />
- Different types of acute and chronic inflammation <br />
- Innate immunity : cellular (phagocytosis and cytotoxicity) and humoral (complement) defensive responses <br />
- Systemic effects of inflammation. <br />
Basic Concepts of immunopathology <br />
- Types of hypersensitivity (type I, II, III, IV) <br />
- Tolerance and autoimmunity : main pathogenetic mechanisms <br />
- Immunedeficiencies and immunedepression <br />
- Stress and immunity <br />
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Full programme
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Bibliography
Recommended text books <br />
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1) Woolf Neville Patologia Generale. Meccanismi della malattia. Idelson-Gnocchi. <br />
2) Kumar V. A. Abbas, N. Fausto: “Robbins e Cotran: Pathologic basis of disease malattie” (2005), Elsevier Saunders, Philadelphia, USA. <br />
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Teaching methods
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Assessment methods and criteria
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Other information
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