Learning objectives
to acquire a deep-rooted theoretical and practical knowledge of the fundamental principles of pharmaceutical formulation
to develop the ability to apply these principles to specific problems in the formulation science;
to acquire a comprehensive understanding of how pharmaceutical dosage forms are developed, manufactured and controlled.
toacquire the independent learning ability required for continuing professional development
Prerequisites
It is preferable to have already passed the exams of ¿general chemistry¿ and ¿organic chemistry¿.
Course unit content
Medicines and pharmaceutical dosage formsItalian and European PharmacopoeiasMetrologyDisperse systems rheologyGood laboratory PracticesPharmaceutical Processes: Particle size reduction, Mixing, Drying, Filtration, Sterilization, Dissolution, GranulationBasic principles of biopharmaceuticspharmacokineticsPharmaceutical ingredients:active principles, excipients, packaging materialsGalenic development: pharmaceutical preformulation and formulation, packagingStability of pharmaceutical productsConventional pharmaceutical dosage- forms: Solid dosage forms (Powders, Granules, Capsules, Tablets,pellets, suppositories), liquid dosage forms (solutions, suspensions,emulsions), semisolid dosage forms (ointments, gels, pastes, creams), sterile productsAdministration routes and pharmaceutical dosage forms: oral, dermatological, parenteral, ocular,auricular, nasal, inhalation, rectal, vaginal.Herbal ExtractsHomeopatic productsSera and vaccinesVeterinary products
Bibliography
P. Colombo, PL Catellani, A. Gazzaniga, E. Menegatti, E. Vidale, Principi di Tecnologie Farmaceutiche, CasaEditrice Ambrosiana, Milano (2004)M. Amorosa, Principi di Tecnica Farmaceutica, Libreria Universitaria L. Tinarelli, Bologna (1998).Farmacopea Ufficiale della Repubblica Italiana, XI Edizione, Istituto Poligrafico e Zecca dello Stato, Roma (2002)
Teaching methods
The course includes theoretical classes and practical works.
