TOXICOLOGY
cod. 03033

Academic year 2010/11
3° year of course - Second semester
Professor
Academic discipline
Farmacologia (BIO/14)
Field
Discipline biologiche
Type of training activity
Characterising
64 hours
of face-to-face activities
8 credits
hub:
course unit
in - - -

Learning objectives

To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.

Prerequisites

Pharmacology exam.

Course unit content

General partFirst principles of toxicityMechanisms and tests of toxicityADME of toxic substanceMetabolism of xenobiotics Cancerogenesis, teratogenesis and mutagenesisSpecial partExperimental toxicology and evaluation of toxicological risksIdiosincrasic and allergic reactions. Interactions between xenobioticsMetals, Solvents, Pesticides, IPA, PCOD, PCBEnviromental toxicoogyAlimentary toxicologyOccupational toxicologyToxicology of biotecnological productsToxicology of herbal productsPoisons and antidotesToxicology of:LungKidneyLiverCardiovascular Sistem Central Nervous Sistem (CNS)

Full programme

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Bibliography


CASARETT & DOULL’S: "Tossicologia: I fondamenti dell’azione delle sostanze tossiche", 6° Edizione. Ed. EMSI, Roma.

Piera Ghi: “Tossicologia: principi e applicazioni all’uso dei farmaci e dei prodotti della salute”. Edizione Minerva Medica

C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”. Edizione Piccin

W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.

GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"

ERNEST HODGSON: “Tossicologia Moderna”, EdiSES

Teaching methods

Traditional lesson

Assessment methods and criteria

oral examination

Other information

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