Learning objectives
To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.
Prerequisites
Pharmacology exam.
Course unit content
General partFirst principles of toxicityMechanisms and tests of toxicityADME of toxic substanceMetabolism of xenobiotics Cancerogenesis, teratogenesis and mutagenesisSpecial partExperimental toxicology and evaluation of toxicological risksIdiosincrasic and allergic reactions. Interactions between xenobioticsMetals, Solvents, Pesticides, IPA, PCOD, PCBEnviromental toxicoogyAlimentary toxicologyOccupational toxicologyToxicology of biotecnological productsToxicology of herbal productsPoisons and antidotesToxicology of:LungKidneyLiverCardiovascular Sistem Central Nervous Sistem (CNS)
Full programme
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Bibliography
CASARETT & DOULL’S: "Tossicologia: I fondamenti dell’azione delle sostanze tossiche", 6° Edizione. Ed. EMSI, Roma.
Piera Ghi: “Tossicologia: principi e applicazioni all’uso dei farmaci e dei prodotti della salute”. Edizione Minerva Medica
C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”. Edizione Piccin
W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.
GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"
ERNEST HODGSON: “Tossicologia Moderna”, EdiSES
Teaching methods
Traditional lesson
Assessment methods and criteria
oral examination
Other information
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