Learning objectives
To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.
Prerequisites
It is recommended to pass the Pharmacology exam or at least to achieved a good preparation on this field.
Course unit content
<br />General part<br />· First principles of toxicity <br />· Mechanisms and tests of toxicity <br />· ADME of toxic substance <br />· Metabolism of xenobiotics <br />· Cancerogenesis, teratogenesis and mutagenesis<br />Special part<br />· Experimental toxicology and evaluation of toxicological risks <br />· Idiosincrasic and allergic reactions. Interactions between xenobiotics <br />· Metals, Solvents, Pesticides, IPA, PCOD, PCB <br />· Enviromental toxicoogy <br />· Alimentary toxicology <br />· Occupational toxicology <br />· Toxicology of biotecnological products <br />· Toxicology of herbal products <br />· Poisons and antidotes<br />Toxicology of:<br />· Lung <br />· Kidney <br />· Liver <br />· Cardiovascular Sistem <br /><br />Central Nervous Sistem (CNS)
Full programme
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Bibliography
<br />CASARETT & DOULL’S: "Tossicologia: fondamenti dell’azione delle sostanze tossiche", Ed. EMSI,<br />Roma.<br />GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"<br />DOLARA: "Tossicologia generale ed ambientale", Ed. Piccin, Padov<br />ERNEST HODGSON: “Tossicologia Moderna”, EdiSES<br />W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.<br />C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”, Piccin
Teaching methods
The oral examination will be about the entire program. Students have to show to have a good comprension of principal parts of each topic.
Assessment methods and criteria
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Other information
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