REGENERATION OF DIFFERENTIATED TISSUES
cod. 1005434

Academic year 2020/21
2° year of course - Second semester
Professor responsible for the course unit
MIRANDOLA Prisco
integrated course unit
8 credits
hub: PARMA
course unit
in ITALIAN

Learning objectives

Gain a detailed understanding on:
functional anatomy of the components that structure the stem cell niches in different organs in the adult;
of structural and functional components of the niches of stem cells and progenitors for regeneration and repair of tissues differentiated;
techniques of isolation, characterization, expansion and differentiation of progenitor osteogenic, chondrogenic, hematopoietic, endocrine organs, skin and eye;
structural, molecular and cellular biomechanis of biomaterials in regenerative medicine

Prerequisites

Humana anatomy and histology

Course unit content

Functional anatomy of the stem cell niche.
The corneal and retinal stem cells.
The epidermal stem cell
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Regenerative medicine in endocrinology: biomaterials and the regeneration of endocrine and neuroendocrine tissues.
Ex situ bioengineering of endocrine and neuroendocrine organs
The skin regeneration techniques: immunobiology and skin regeneration.
Techniques of oral tissue regeneration
Biomaterials and implant prosthetics and tissue regeneration in periodontology
Techniques of bone regeneration
The biomechanic, structure, molecular and cellular properties of the bone
The osteogenic molecules in the regeneration and / or the ossteointegration between bones and stromal cells and biomaterials.
Regeneration techniques in eye diseases
New techniques in corneal transplantation.

Full programme

Functional anatomy of the stem cell niche.
The corneal and retinal stem cells.
The epidermal stem cell
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Regenerative medicine in endocrinology: biomaterials and the regeneration of endocrine and neuroendocrine tissues.
Ex situ bioengineering of endocrine and neuroendocrine organs.
The skin regeneration techniques: immunobiology and skin regeneration.
Techniques of oral tissue regeneration
Biomaterials and implant prosthetics and tissue regeneration in periodontology
Techniques of bone regeneration
The biomechanic, structure, molecular and cellular properties of the bone.
The osteogenic molecules in the regeneration and / or the ossteointegration between bones and stromal cells and biomaterials.
Regeneration techniques in eye diseases
New techniques in corneal transplantation.

Bibliography

International reviews and scientific commentaries will dispensed by the teacher
issues.

Teaching methods

The course will be held through lectures to Students either in the classroom (“in presenza”) or in synchronous-streaming (“in telepresenza”) on the Teams platform. Therefore, the opportunity of Student/Teacher interaction will be preserved both face to face and remotely, by the simultaneous use of the Teams platform.
Lectures will be supported by slide presentations, which will be available to students on the Elly platform (https://elly2020.medicina.unipr.it/).

Assessment methods and criteria

Written examination, multiple choice test.
In case of the persistence of the health emergency, the exams will be conducted remotely, as follows:
structured written test conducted remotely (by Teams and Elly). The test consists of 30 multiple choice questions on the course contents (reference texts + documents uploaded to Elly during the course). There is no penalty for incorrect answers.
The final mark, reported directly on Esse3, will correspond to the arithmetic average of the assessments obtained in the written test.
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes

Other information

- - -