Learning objectives
Learning laboratory organization to the purpose of a proper interactions between facilities (hospital ward-lab).
Learning of analytical procedures steps, with particular focus to the preanalytical phase (sample collection, storage, processing and transporting biological samples). Acquiring knowledge on the main clinical biochemistry analyses and execution approaches of the analytical processes). Acquiring knowledge on the main diagnostic profiles, with special focus on pregnancy screenings which can be requested.
Prerequisites
Course unit content
Laboratory organization. The analytical phase. The biological sample. Types of interference. Types of clinical biochemistry tests and analytical approaches. Analytical profiles of functionality or of injuries to major organs and systems. Analytical profiles during pregnancy.
Full programme
The diagnostic laboratory process: organizational elements. The preanalytical phase: patient preparation, sample’s collection, treatment and storage. Clinical chemistry laboratory analysis: qualitative, quantitative, semiquantitative.
Immunochemistry principles.
Quality of the results. Internal and external quality control. Analytical and post analytical variables. Estimate of their clinical impact. Laboratory analysis during pregnancy. Presentation of the main diagnostical profiles. Principles of diagnostic hematology, notes on hemostasis. Main enzymatic determinations and related clinical use.
Biomarkers of cardiac functionality. Laboratory indexes of functional and ischemic damage. Parameters of hepatic and renal functionality.
Bibliography
Costantini W., Calistri D., Ostetrica. Le basi scientifico - culturali. Vol. 1-2-3. Ed. Piccin, 2013.
M.Galzigna, M.Plebani. Biochimica Clinica Generale. Edit. Piccin. M.Ciaccio, G.Lippi. Biochimica Clinica e Medicina di Laboratorio. EdiSES (2017).
Ministero della salute: Linee Guida della gravidanza fisiologica (2011).
Linee guida per lo screening prenatale della trisomia 21.
Biochimica Clinica 2011; 35(3) 229.
01 Aprile 2015 “Raccomandazioni per l’esecuzione del test da Carico Orale di Glucosio (OGTT)” GdS Diabete Mellito, Documenti ufficiali, SIBIOC.
Teaching methods
Frontal and interactive lessons.
Assessment methods and criteria
The achievement of the learning tasks will be assessed by an oral / written evaluation related to the covered topics. The questions will assess students’ knowledge and understanding of the contents, and if he is able to apply the knowledge acquired in the practice of the profession. Failed answer to one or more questions or proved insufficiency of the basic knowledge on the subject will preclude the successful completion of the exam. In case of completion of the exam, an evaluation that contributes to the final grade of the course will be defined and it will be based on the achievement of the objectives.
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