Learning objectives
This practical part of the course of EXPERIMENTAL PHARMACOLOGY aims at enabling the student TO KNOW AND UNDERSTAND the different experimental models applied to assess the therapeutic efficacy of new potential drugs and to develop the student's ability TO USE THE KNOWLEDGE AND UNDERSTANDING ACQUIRED, so that at the end of the course he will be able to choose the experimental models to be used in drug characterization and to analyze and correctly interpret the results of virtual experiments demonstrating INDEPENDENCE OF JUDGMENT, LEARNING ABILITY AND COMMUNICATION
Prerequisites
Basic knowledge of Pharmacology and Pharmacotherapy
Course unit content
One part of the practical lessons of EXPERIMENTAL PHARMACOLOGY concerns:
production and acquisition of experimental results processing statistical analysis through the application of descriptive and inferential principles.
Participation in pharmacological experimentations at different degree of complexity.
Full programme
This part of the course consists of:
Participation in experiments carried out in the laboratory as part of specific research programs. During this activity the student can learn the features and the properties of the experimental models used in pharmacology.
Application of statistical tests for the analysis of experimental data:
the frequency distribution curve, the confidence limits of the mean, parametric (t-test, analysis of variance) and non-parametric tests, linear regression analysis, Schild analysis.
Bibliography
Teaching material is made available by the teacher in electronic copy
GOODMAN & GILMAN S. The Pharmacological Basis of Therapeutics McGraw-Hill
DOLARA P, FRANCONI E, MUGELLI A: Farmacologia e Tossicologia Sperimentale Pitagora Editrice, Bologna.
PAOLETTI R et al: Farmacologia generale e molecolare UTET
KENAKIN T: A Pharmacology Primer, Elsevier
Teaching methods
The teaching is done through the participation of students in individual and group exercises in virtual experiments performed in classroom, in statistical analysis of data and observation of experiments conducted in the laboratory.. Groups of students are invited and driven in the organization and presentation of seminars, through consultation of bibliographic sources. These activities are designed to reinforce in each student the ability TO INTEGRATE KNOWLEDGE, TO ANALYZE CRITICALLY complex issues and TO COMMUNICATE clearly their own conclusions.
Assessment methods and criteria
The assessment of the achievement of the objectives of the course consists of an oral examination. Through questions regarding the theoretical content of the course it will be determined whether the student has achieved the goal of KNOWLEDGE AND UNDERSTANDING of the methodological approach to be used in pharmacological experimentation and statistical analysis of data. Through questions regarding virtual experimental situations it will be determined whether the student has the ability of APPLYING THE ACQUIRED KNOWLEDGE and to solve new and complex problems through arguments that demonstrate the ACQUISITION OF LEARNING SKILLS, FORMULATION OF AUTONOMOUS JUDGMENTS and ABILITY TO COMMUNICATE.
Other information
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