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Università degli Studi di Parma Università degli Studi di Parma
Second cycle degree course in
Medical, veterinary anf pharmaceutical biotechnologies
Università degli Studi di Parma
Department of Medicine and Surgery

PHARMACEUTICAL BIOCHEMISTRY
cod. 23806

Academic year 2015/16
1° year of course - First semester
Professor
Academic discipline
Biochimica (BIO/10)
Field
Discipline biotecnologiche comuni
Type of training activity
Characterising
42 hours
of face-to-face activities
6 credits
hub: PARMA
course unit
in - - -
lectures timetable unavailable
exam calls

Integrated course unit module: INTERACTION DRUG-BIOMOLECULES

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Learning objectives

The course aims at providing students with the molecular basis for the
understanding of the interaction between biological macromolecules and ligands, with a focus on drug targets.

Prerequisites

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Course unit content

Definition of drug and drug target
Binding properties of proteins
Enzymes as drug target
Treatment of HIV and NSAIDs as examples of the therapeutic use of enzyme inhibitors
Receptors as drug targets
Recombinant drugs

Full programme

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Bibliography

David L. Nelson, Michael M. Cox
I PRINCIPI DI BIOCHIMICA DI LEHNINGER 5 ed, ZANICHELLI

Copeland R. Evaluation of enzyme inhibition in drug discovery, Wiley.

Teaching methods

The topics of the course will be delivered with oral presentations associated with informatics tools and visits to laboratories

Assessment methods and criteria

The exam is either a written "in itinere" test or a final oral test.
The written test will take place during the teaching semester and will consist of two tests, dealing with the first and second part of the programm, respectively. The teaching module final mark is the average of the marks of the two tests.
The oral test is given together with the test for the biological physical chemistry module during the exam periods.

Other information

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