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University of Parma
Course catalogue
Università degli Studi di Parma
course catalogue

NEOPLASTIC DISEASES
cod. 1000190

borrowed from Corso di TIPO in CDS 1109 - MALATTIE NEOPLASTICHE - cod. 1000190
Academic year 2007/08
1° year of course - Second semester
Professor
Academic discipline
Patologia generale (MED/04)
Field
Discipline mediche e riproduzione umana
Type of training activity
Characterising
10 hours
of face-to-face activities
1 credits
hub:
course unit
in
lectures timetable unavailable
exam calls

Integrated course unit module: THE MOLECULAR MECHANISMS OF DISEASE

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Learning objectives

To provide the bases for the comprehension of the molecular pathogenesis of neoplastic disease and its treatment.

Prerequisites

Knowledge of basic biochemistry and cell biology is required

Course unit content

<p> Biology of tumor growth: bening versus malignant neoplasms <br />
Molecular basis of cancer: <br />
• The normal cell cycle <br />
• Self-sufficiency in growth signals: oncogenes <br />
• Insensitivity to growth inhibitory signals: tumor suppressor genes <br />
• Evasion of apoptosis <br />
• DNA repair defects and genomic instability in cancer cells <br />
• Limitless replicative potential: telomerase <br />
• Development of sustained angiogenesis <br />
• Invasion and metastasis <br />
• Stromal microenvironment and carcinigenesis <br />
</p>

Full programme

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Bibliography

Chapter 7 of Robbins and Cotran "Pathologic basis of diseases" is a full comprehensive text. Proper reference to the texts of biochemistry and cell biology used in previous courses is recommended. Lectures will be supported by slides and scientific literature, which will be provided to the students.

Teaching methods

Oral lessons (slides and scientific literature will be used during the lessons) . <br />
The tutorials will be provided to the students. <br />
Oral examination (with discussion of scientific literature). <br />

Assessment methods and criteria

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Other information

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