Learning objectives
<p>Acquisition of essential knowledge about currently available biotechnogical vaccines and experimental biotechnological approaches for the rationale design of new vaccines against infectious diseases.</p>
<p>Acquisition of the current viral gene manipulation techniques relative to gene therapy.</p>
Prerequisites
Students are required to have a knowledge of basic molecular biology.
Course unit content
<p>Currently available biotechnogical vaccines and vaccine technologies. Experimental biotechnological approaches for the rationale design of new vaccines against infectious diseases.</p>
<p>Viral Vectors in gene therapy and immunotherapy. Retrovirus: <br />
a) Molecular aspects of replication <br />
b) Vector structure: oncoretrovirus (MMLV) and lentivirus (HIV) <br />
c) Packaging strategies <br />
d) Targeting and pseudo-typification strategies and mechanisms (VSV-G) <br />
e) Cell transduction and expression control.<br />
</p>
Full programme
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Bibliography
Scientific reviews on specific topics. Lecture notes.
Teaching methods
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Assessment methods and criteria
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Other information
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