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Università degli Studi di Parma Università degli Studi di Parma
Second cycle degree course in
Medical, veterinary anf pharmaceutical biotechnologies
Università degli Studi di Parma
Department of Medicine and Surgery

PHARMACEUTICAL BIOCHEMISTRY
cod. 23806

Academic year 2013/14
1° year of course - First semester
Professor
Academic discipline
Biochimica (BIO/10)
Field
Discipline biotecnologiche comuni
Type of training activity
Characterising
42 hours
of face-to-face activities
6 credits
hub: -
course unit
in - - -
lectures timetable unavailable
exam calls

Integrated course unit module: INTERACTION DRUG-BIOMOLECULES

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Learning objectives

The course is aimed at providing students the knowledge of the molecular bases of the interaction between drugs and proteins with the goal of the understanding the detreminants controlling specificity and affinity.

Prerequisites

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Course unit content

Definition of chemical space, and principles of protein-ligand (drug) recognition. Enzymes as drug targets.
Receptors as drug targets.
Channels and transmembrane proteins as drug targets.
Blood substitutes.
Computational and experimental methods for the investigation of protein-drug recognition.

Full programme

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Bibliography

David L. Nelson, Michael M. Cox
I PRINCIPI DI BIOCHIMICA DI LEHNINGER 5 ed, ZANICHELLI

Teaching methods

The topics of the course will be delivered with oral presentations associated with informatics tools and visits to laboratories

Assessment methods and criteria

The evaluation of the candidate will take place with an oral exam aimed at evaluating the knowledge of the candidate on the course program and hher/his understanding of the principles that control the protein-drug recognition. The oral exam will be held at the same time for both modules.

Other information

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