Learning objectives
The aim of the course is to review fundamentals and provide an up-to-date account of current knowledge in biology and pathophysiology of articular cartilage tissue focusing on the cartilage repairing. With a practical approach during the lab classes the students will acquire a core professional training in primary cell culture methods and techniques and also they will acquire capacity to apply systems to culture articular chondrocytes and to maintain chondrocyte differentiation. <br />
Prerequisites
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Course unit content
Osteochondrogenesi (Module A) <br />
Lecturer: Prof. Paolo Borghetti (VET/03) <br />
(CFU: 1 CFU lesson (8 hours) + 1 CFU praticals (8 hours) <br />
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Theory: <br />
Anatomy , histology and biomechanics of articular joints. Structure, biology and metabolism of the articular cartilage. <br />
Physiopathology of the tissue cartilage metabolism. The molecular basis of chondrocyte differentiaiton and chondrogenesis. Biomaterials for cartilage reparing <br />
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Practicals: <br />
Isolation of chondrocytes from articular cartilage tissue. <br />
Adhesion and tridimensional models of primary chondrocyte culture. <br />
Tecnique for the maintainance of the differentiation of articular chondrocytes in culture. <br />
Full programme
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Bibliography
1) Scientific reviews on the topics of the course <br />
2) Lab experimental protocols <br />
Teaching methods
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Assessment methods and criteria
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Other information
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