HUMAN AND MODEL ORGANISMS MOLECULAR GENETICS GENOTOXICITY
Course unit partition: Primo Semestre

Academic year 2009/10
1° year of course - First semester
Professor
Academic discipline
Genetica (BIO/18)
Field
Ambito aggregato per crediti di sede
Type of training activity
Caratterizzante
72 hours
of face-to-face activities
9 credits
hub: PARMA
course unit
in - - -

Learning objectives

Aims of the course is the study of genetic approaches applied to genomics and functional analysis in eukaryotes. Particular attentions will be paied to yeast, a model organism in fundamental and biotechnologic applications.

Prerequisites

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Course unit content

 YEAST AS MODEL ORGANISM <br />
Forward e reverse genetics- Genome sequencing in S. cerevisiae- Comparative genomics in yeasts- S. cerevisiae deletant collection and use of null mutants in functional analysis- Methods for gene interaction studies applied to human diseases - Yest as model organism for the study of mitochondrial genetics- Yeast as model organism for the study of mitochondrial diseases. <br />
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FUNCTIONAL ANALYSIS IN PLANTS <br />
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Caenorhabditis elegans AS MODEL ORGANISM <br />
Forward e reverse genetics in C. elegans. Functional analysis by RNAi - C. elegans as model organism for the study of human pathologies. <br />

Full programme

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Bibliography

Original papers selected by the teacher

Teaching methods

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Assessment methods and criteria

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Other information

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