Learning objectives
The objective of the course is to understand the basic concepts of enzymology such as: chemical and enzymatic kinetics, transition state theory, enzyme reaction types, enzymes, single and multi-layered enzymes, enzyme tests. The course also aims to introduce students to the possible industrial and/or medical applications where enzymes play a decisive role. <br />
At the end of the course the student should have a clear understanding of the theory underlying enzymatic activity and a clear vision of biocatalytic applications in the world of work. <br />
Prerequisites
<p>none</p>
Course unit content
- Brief history of enzymology <br />
- Transition state theory <br />
- Chemical and enzymatic catalysis <br />
- Examples of enzymes <br />
- Enzymatic kinetics <br />
- Factors which influence enzymatic reactions <br />
- Enzymatic inhibition <br />
- Cooperativity <br />
- Multi-layered kinetics <br />
- Industrial applications <br />
- Biocatalysis <br />
- Immobilised enzymes <br />
- Protein engineering <br />
Full programme
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Bibliography
ENZYMES, a Practical Introduction to Structure, Mechanism, and Data Analysis, SECOND EDITION, Robert A. Copeland. <br />
<br />
Fersht, A "Struttura e meccanismi d'azione degli enzimi" Ed. Zanichelli. <br />
Teaching methods
Written examination.
Assessment methods and criteria
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Other information
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