Learning objectives
The course aims to enable the student to acquire the knowledge and the understanding of the basic principles of organic synthesis applied to medicinal chemistry and the main techniques used in the synthesis of bioactive compounds. The aim is to provide the student with an adequate capacity applying the knowledge and the understanding acquired for the solution of the main problems in the field of synthesis and purification of bioactive compounds.
Prerequisites
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Course unit content
Lectures will deal with organic synthesis applied to the medicinal chemistry, with particular attention to innovative techniques and green chemistry. The course also provides practical exercises carried on in laboratory regarding the synthesis and purification of small bioactive compounds.
Full programme
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Bibliography
• I. VOGEL “Chimica Organica Pratica”, Casa Editrice Ambrosiana, Milano.
• D. PAVIA, G. LAMPMAN, G. KRIZ “Il Laboratorio di Chimica Organica”, Ed. Italiana a cura di P. Grunanger, D. Pocar; Sorbona.
• M. D’ISCHIA “La Chimica Organica in Laboratorio”, Piccin.
Teaching methods
The lectures cover the main techniques of organic synthesis for the preparation and purification of biologically active compounds. The course is supported by laboratory exercises. These exercises will be individual and practical and will give the opportunity to each student to approach independently the solution to different syntheses and purifications of compounds of pharmaceutical interest.
Assessment methods and criteria
The assessment of the achievement of the objectives consists of an oral exam. The questions will cover both the theoretical aspects and the practical in laboratory ensuring in this way the knowledge and the understanding of the student and the his capability in applying such knowledge and understanding to the solution of problems concerning the synthesis and purification of compounds of pharmaceutical interest.
Other information
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