Learning objectives
Objectives of the course (preferably expressed in terms of learning outcomes and competences):
To give the basic notions about
- the technological process
- the origin of the drugs
- the chemistry of the active compounds
- the pharmacological activity and the therapeutic applications of the main drugs
Prerequisites
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Course unit content
GENERALITIES
Medicinal plant and crude drug.
Phytocomplex and active compounds. Interactions.
Toxicity of natural preparations.
Basics of general pharmacology: pharmacokinetic and pharmacodynamic
Traditional medicine and phytotherapy.
Technology of natural medical products:
- harvesting, drying, grinding, squeezing, enfleurage, distillation, extraction.
Drug acquisition and preservation.
Galenical preparations.
VEGETAL ACTIVE PRINCIPLES:
- glycosides (cardioactive, cyanogenics, sulphurated, antraquinones, saponins).
- alkaloids: purinergics, tropanics, benzylisoquinolics, indolics, quinolinics.
- lipids: oils, fats, waxes.
- phenilpropanoids: flavonoids, lignans, tannins.
- terpenes: essences, resins, balms.
- carbohydrates: mono/polysacchrides, gums, mucilages, pectins.
THERAPEUTIC APPLICATIONS
Drugs acting on gastrointestinal system
- Aloe spp, Matricaria recutita, Althaea officinalis, Glycyrrhiza glabra, Foeniculum vulgare, Pimpinella anisum, Illicium verum.
- Constipation: manna, Rhamnus frangula, Rhamnus purshiana, Cassia spp, Aloe spp, Rheum spp.
Drugs acting on CNS
- Stimolants: Coffea arabica, Thea sinensis, Theobroma cacao, Cola spp, Ilex paraguayensis, Paullinia cupana
- Sedatives: Valeriana officinalis, Matricaria recutita
- Anxyolitics: Passiflora incarnata, Melissa officinalis, Piper methysticum, Valeriana officinalis. Humulus lupulus
- Antidepressants: Hypericum perforatum, Rhodiola rosea, Eleuterococcus senticosus, Lepidium meyenii.
- Other:Panax ginseng, Gingko biloba
Drugs acting on cardiovascular system
- Antihyperlipidemic plants: Cynara scolimus, Allium sativum, Vaccinium myrtillus, Commiphora mukul.
- Peripheral vascular disorders : Aesculus hippocastanum, Cupressus sempervirens, Hamamelis virginiana, Vaccinium myrtillus, Melilotus officinalis, Ruscus aculeatus
Drugs acting on respiratory system
- saponins: Marrubium vulgare,Hedera helix, Poligala senega.
- essences: Eucaliptus globulus, Melaleuca spp, Menta piperita, Lavandula officinalis, Pimpinella anisum, Foeniculum vulgare, Myroxylon pereire, Myroxylon balsamum.
- mucilages: Plantago lanceolata, Althaea officinalis.
Adaptogenic and immunostimulant plants: Eleuhterococcus senticosus, Panax ginseng, Echinacea angustifolia.
Antinflammatory drugs.
Herbal chemotherapeutics.
Full programme
GENERALITIES
Medicinal plant and crude drug.
Phytocomplex and active compounds. Interactions.
Toxicity of natural preparations.
Basics of general pharmacology: pharmacokinetic and pharmacodynamic
Traditional medicine and phytotherapy.
Technology of natural medical products:
- harvesting, drying, grinding, squeezing, enfleurage, distillation, extraction.
Drug acquisition and preservation.
Galenical preparations.
VEGETAL ACTIVE PRINCIPLES:
- glycosides (cardioactive, cyanogenics, sulphurated, antraquinones, saponins).
- alkaloids: purinergics, tropanics, benzylisoquinolics, indolics, quinolinics.
- lipids: oils, fats, waxes.
- phenilpropanoids: flavonoids, lignans, tannins.
- terpenes: essences, resins, balms.
- carbohydrates: mono/polysacchrides, gums, mucilages, pectins.
THERAPEUTIC APPLICATIONS
Drugs acting on gastrointestinal system
- Aloe spp, Matricaria recutita, Althaea officinalis, Glycyrrhiza glabra, Foeniculum vulgare, Pimpinella anisum, Illicium verum.
- Constipation: manna, Rhamnus frangula, Rhamnus purshiana, Cassia spp, Aloe spp, Rheum spp.
Drugs acting on CNS
- Stimolants: Coffea arabica, Thea sinensis, Theobroma cacao, Cola spp, Ilex paraguayensis, Paullinia cupana
- Sedatives: Valeriana officinalis, Matricaria recutita
- Anxyolitics: Passiflora incarnata, Melissa officinalis, Piper methysticum, Valeriana officinalis. Humulus lupulus
- Antidepressants: Hypericum perforatum, Rhodiola rosea, Eleuterococcus senticosus, Lepidium meyenii.
- Other:Panax ginseng, Gingko biloba
Drugs acting on cardiovascular system
- Antihyperlipidemic plants: Cynara scolimus, Allium sativum, Vaccinium myrtillus, Commiphora mukul.
- Peripheral vascular disorders : Aesculus hippocastanum, Cupressus sempervirens, Hamamelis virginiana, Vaccinium myrtillus, Melilotus officinalis, Ruscus aculeatus
Drugs acting on respiratory system
- saponins: Marrubium vulgare,Hedera helix, Poligala senega.
- essences: Eucaliptus globulus, Melaleuca spp, Menta piperita, Lavandula officinalis, Pimpinella anisum, Foeniculum vulgare, Myroxylon pereire, Myroxylon balsamum.
- mucilages: Plantago lanceolata, Althaea officinalis.
Adaptogenic and immunostimulant plants: Eleuhterococcus senticosus, Panax ginseng, Echinacea angustifolia.
Antinflammatory drugs.
Herbal chemotherapeutics.
Bibliography
Bibliografia consigliata: M. Tognolini, M. Chiavarini - Principi di farmacognosia e fitoterapia - UNINOVA
Teaching methods
Oral lessons
Assessment methods and criteria
Oral examination
Other information
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