Learning objectives
The student will achieve the fundamental knowledge on cell pathology, injury responses and cell death. Causes and mechanisms of genetic diseases (single-gene disorders) will be treated to simplify the knowledge of gene therapy principles. The subject “Cancer” will be face from molecular, cellular and histological point of view to offer a panorama of the potential biotechnological applications.
Prerequisites
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Course unit content
1. Cell injury and cell death
2. Cellular pathology: Cellular adaptation; Intracellular accumulations; Cellular aging
3. Tissue responses to injury: Acute and chronic inflammation; Tissue repair – regeneration, healing; Fibrosis
4. Genetic disorders: Transmission patterns of single-gene disorders; Biochemical and molecular basis of single-gene disorders; Some example of single-gene disorders
5. Neoplasia: Morphologic and biologic properties of tumor cells; The molecular basis of cancer; Tumor progression, invasion and metastasis; Benign and malignant neoplasms; Principles of tumor classification
Full programme
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Bibliography
Robbins - Pathologic basis of disease
Teaching methods
frontal lesson
Assessment methods and criteria
written examination
Other information
Didactic material available on-line
