DESIGN OF BIOTECHNOLOGICAL VACCINES AND VIRAL VECTORS UNIT A
cod. 1000217

Academic year 2010/11
1° year of course - Second semester
Professor
Academic discipline
Microbiologia e microbiologia clinica (MED/07)
Field
Discipline biotecnologiche comuni
Type of training activity
Characterising
16 hours
of face-to-face activities
2 credits
hub: -
course unit
in - - -

Integrated course unit module: BIOTECHNOLOGICAL TECHNIQUES

Learning objectives

Acquisition of essential knowledge about: Principles of anti-infective vaccinology. Relevant existing vaccines. Biotechnological vaccines: characteristics and development. Existing biotechnological tools in vaccinology.

Prerequisites

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Course unit content

Principles and immunological basis of vaccinology. Relevant available anti-infective vaccines (live-attenuated, killed-inactivated, subunit, purified or conjugated antigens, toxoids, recombinant) or experimental (DNA, anti-idiotypic). Biotechnological vaccines and their design: characteristics and development. Existing biotechnological vaccines (HBV, HPV, Rotavirus, polysaccharide-conjugated vaccines). Rational design. Reverse vaccinology. Recombinant bacteriophges and bacteria as vaccines and vaccine delivery veicles. Plant-based vaccines. Adjuvants and delivery systems.

Full programme

Principles and immunological basis of vaccinology. Relevant available anti-infective vaccines (live-attenuated, killed-inactivated, subunit, purified or conjugated antigens, toxoids, recombinant) or experimental (DNA, anti-idiotypic). Biotechnological vaccines and their design: characteristics and development. Existing biotechnological vaccines (HBV, HPV, Rotavirus, polysaccharide-conjugated vaccines). Rational design. Reverse vaccinology. Recombinant bacteriophges and bacteria as vaccines and vaccine delivery veicles. Plant-based vaccines. Adjuvants and delivery systems.

Bibliography

Lectures notes. Reviews on specific topics.

Teaching methods

Oral lessons

Assessment methods and criteria

Oral exam

Other information

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