Learning objectives
The objectives are the knowledge and development of research methods and an overview of currently used methods.
Prerequisites
Genetics, Molecular Genetics, Cell Biology
Course unit content
The course aims to analyse the genetic bases of differentiation and development control, by use of model organisms chosen on the basis of their peculiarity. Moreover the course aims to identify, by using model organism,the contribute of genetics information on gene expression and development.
Full programme
Developmental Genetics
Eukaryotic model organisms
The cell cycle in yeasts, molluscs, amphibians and echinoderms, Homo sapiens and check point mechanisms.
Control of the pheromone signalling pathway in S. cerevisiae
Control of apoptosis in Caenorhabtidis elegans
Control of development in Drosophila melanogaster
Epigenetics
Eukaryotic model organisms
Silencing, Imprinting, Dosage compensation
Bibliography
Course materials provided by the professor -Chapters of genetics texts regarding Developmental Genetics
Carrol et al. Dal DNA alla diversita - Evoluzione molecolare del progetto corporeo animale Ed. Zanichelli
Allis et al. Epigenetics Marie-Laure Caparassos Ed.
Teaching methods
For each process, genetic dissection, or rather the analysis of genes whose products control the process itself, will be carried out with attention focused on the methods used for identifying the genes and emphasis on areas of uncertainty and gaps in knowledge as well as known aspects.
Assessment methods and criteria
Oral examination. Assessment can be integrated with the presentation of a paper on an agreed research topic.
Other information
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