Course catalogue | University of Parma

Professor
Academic discipline: Genetica (BIO/18)
Field: Discipline del settore biomolecolare
Type of training activity: Characterising

24 hours
of face-to-face activities

6 credits

hub: PARMA

course unit
in - - -

lectures timetable unavailable

exam calls

Learning objectives

Knowledge of the mechanism of the microevolution. Knowledge of the multivariate statistical methods usually adopted in the field of population genetics

Prerequisites

Good knowledge of genetics, mathemarics and statistics

Course unit content

Human populations genetics

Full programme

First part

The law of Hardy-Weinberg
Heterozyote/homoygote advantage at the CCR5 locus
Heterozyote advantage at the beta-globin locus
Identification of the thalassaemia carriers by discriminant analysis
Distance between population by the Mahalanobis index
Effects of mutation, natural selection, gene flow and random genetic drift on the allele frequencies
Microevolution and sympatric speciation in Ragholetis pomonella
Genetic variability between and within populations by the Wright fixation index
Genetic distance between populations, matrix of genetic distance, principal components analysis: genetic history of Italy, Europe, and Continents
Molecular clock and evolution of Primates
Origin of anatomically modern humans from sequence analysis of mitochondrial DNA and Alu repeats
Correspondence analysis

Second part
Genetic diversity
Evolutionary genetics of natural populations
Genetics and decrease of population size
Genetics and extinction
Resolution of the taxonomic ambiguities
Forensic molecular genetics

Bibliography

Human Evolutionary Genetics, M.A. Joblings, M.E. Hurles, C.Tyler-Smith

Teaching methods

Frontal lessons and practical with genetic databases.

Assessment methods and criteria

Oral exam

Other information

Is appreciated a good knowledge of the English language

POPULATION GENETICS cod. 02615